In this retrospective study of 191 adults who underwent single cord blood transplantation (CBT), researchers found that donor/recipient sex compatibility did not have a significant impact on survival. A multivariate analysis using female donor/female recipient transplants as the reference revealed that female/male transplants had a higher incidence of extensive chronic GVHD (hazard ratio (HR): 2.97, p=0.02) and male/female transplants had a lower incidence of platelet engraftment (HR: 0.56, p=0.02). Despite these differences, there was no increase in mortality following sex-mismatched CBT.
Konuma T, et al. Bone Marrow TransplantChoose a Topic
- All Topics
- Unrelated Donor HCT
- AML
- Patient Eligibility
- Post-Transplant
- CIBMTR Publications
- GVHD
- ALL
- Lymphomas and CLL
- Preparative Regimens
- Pediatric HCT
- Older Patient HCT
- MDS
- Non-Malignant Disorders
- BMT CTN Publications
- Cord Blood
- Multiple Myeloma
- Sickle Cell Disease
- HLA Matching
- ASH 2015
- ASH 2017
- ASH 2016
- ASH 2020
- CML
- ASH 2018
- Neuroblastoma
Identifying Impact of Donor/Recipient Sex Match in Cord Blood Transplant
Mar 2014