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Recent Research

Stay up-to-date on the advancing field of HCT with short summaries and links to the most relevant published research.

  • Updated evidence-based guidelines for optimal selection of unrelated donors and cord blood units for HCT

    September 2019

    Dehn J, et al., Blood – A panel of immunogeneticists and other experts in the field of hematopoietic cell transplantation (HCT) has published updated evidence-based guidelines for the optimal selection of unrelated donors and cord blood units used for transplants.

    The updated guidelines make recommendations for both HLA and non-HLA factors to consider in graft selection, including donor availability, donor age, patient sensitivity to HLA antigens, natural killer (NK) cell alloreactivity, and minimum total nucleated cell doses and CD34+ cell doses for cord blood units.

     

    Read More

  • New Analysis Determines HLA Match Rates in Be The Match Registry

    January 2016
    Buck K, et al. Biol Blood Marrow Transplant – A new analysis of the Be The Match Registry has determined that 7/8 HLA match rates are >80% for all four of the most frequent patient race/ethnic groups in the United States – White (WH), Hispanic (HIS), Asian/Pacific Islander (AIP), and African American (AFA).

    Read More

  • GVHD Marker Found in HLA-DPB1 Mismatched HCT

    September 2015
    Petersdorf EW, et al. N Engl J Med –In this study of 2,029 transplants reported to CIBMTR (Center for International Blood and Marrow Transplant Research), researchers found that an HLA-DPB1 mismatch is not sufficient by itself to lead to GVHD, but is dependent upon specific DPB1 allele variations in both the donor and the recipient.

    Read More

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Transplant Indications and Outcomes

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Choose a Topic

  • All Topics
  • ASH 2017
  • AML
  • MDS
  • Lymphomas and CLL
  • Older Patient HCT
  • Sickle Cell Disease
  • Post-Transplant
  • GVHD
  • Patient Eligibility
  • CIBMTR Publications
  • Cord Blood
  • Pediatric HCT
  • ALL
  • CML
  • Multiple Myeloma
  • Neuroblastoma
  • Non-Malignant Disorders
  • HLA Matching
  • Preparative Regimens
  • BMT CTN Publications
  • Unrelated Donor HCT
  • ASH 2018
  • ASH 2020