According to results of a randomized, multicenter study, hematopoietic cell transplant (HCT) patients receiving post-transplant survivorship care plans (SCPs) had significantly lower levels of cancer treatment distress, compared to HCT recipients receiving routine post-transplant care.
Researchers studied 458 adult HCT survivors from 17 transplant centers who were 1-5 years post-transplant, proficient in English and without relapse or second cancers. To increase generalizability, recipients with any diagnosis, HCT/donor type and conditioning regimen were eligible.
SCPs were automatically generated using patient-specific clinical data submitted by transplant centers to the CIBMTR® (Center for International Blood and Marrow Transplant Research®). Individualized SCPs included specific patient risk factors and treatment exposures, including age, sex, HCT type, graft-versus-host disease (GVHD), and use of total body irradiation or steroids.
Patients were then randomized to SCP (n=231) or routine care (n=227) per their transplant center.
Baseline and phone surveys at 2 weeks and 6 months assessed patient-reported outcomes, and measured cancer treatment distress, knowledge of transplant exposures, health behaviors, confidence in survivorship information, health care utilization and general health self-efficacy.
The significant reduction in cancer treatment distress in transplant recipients receiving SCPs was independent of sex, transplant type, graft-versus-host disease (GVHD) status, diagnosis and health literacy.
The researchers concluded that automatically generated individualized SCPs based on patient risk factors and treatment exposures can be generated from a centralized clinical registry and that this method of creating SCPs can reduce the burden on health care professionals to create such plans.