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Recent Research

Stay up-to-date on the advancing field of HCT with short summaries and links to the most relevant published research.

  • Cyclophosphamide is Effective GVHD Prophylaxis in Matched Related and Unrelated HCT

    November 2021
    Ruggeri A, et al. ASH abstract oral presentation, December 2017 – In patients with acute leukemia, post-transplant cyclophosphamide (PT-Cy) can effectively control GVHD after matched related and unrelated donor HCT, and is even more effective when combined with 1 or 2 immunosuppressive drugs.

    Read More

  • Survivorship Care Plans for HCT Recipients Reduce Cancer Treatment Distress

    December 2017
    Majhail NS, et al. ASH abstract oral presentation, December 2017 – According to results of a randomized, multicenter study, hematopoietic cell transplant (HCT) patients receiving post-transplant survivorship care plans (SCPs) had significantly lower levels of cancer treatment distress, compared to HCT recipients receiving routine post-transplant care.

    Read More

  • HCT Significantly Improves Quality of Life in Children with Sickle Cell Disease

    December 2017
    Bernaudin F, et al. ASH abstract oral presentation, December 2017 – Children with sickle cell disease (SCD) have significantly better physical health and school functioning after transplantation than do those receiving chronic transfusion, according to results of a donor/no donor study of 67 patients with SCD.

    Read More

  • Early Detection of WT1 Minimal Residual Disease Predicts Outcomes in AML

    December 2017
    Lambert J, et al. ASH abstract oral presentation, December 2017 – Using Wilms’ tumor gene (WT1) expression as a marker for minimal residual disease (MRD) in patients with acute myeloid leukemia (AML) is a powerful prognostic factor in treatment selection, according to a study of 713 patients with AML.

    Read More

  • Molecular MRD Detection by NGS Predicts Relapse and Survival in Adults with AML

    December 2017
    Jongen-Lavrencic M, et al. ASH abstract oral presentation, December 2017 – A study of 482 adults with newly diagnosed AML has demonstrated that prospective molecular minimal residual disease (MRD) detection by next-generation sequencing (NGS) of residual leukemia defined by non-DTA mutations in complete remission (CR) is an independent predictor for relapse and survival.

    Read More

  • Lower Relapse and Improved Survival with Mild Acute GVHD after HCT for ALL

    December 2017
    Yeshurun M, et al. ASH abstract oral presentation, December 2017 – A large-scale multicenter study of pediatric and adult patients with acute lymphoblastic leukemia (ALL) has confirmed that HCT imparts a potent graft-versus-leukemia effect in ALL with improved survival and lower relapse in patients who experience grade I-II acute GVHD.

    Read More

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Choose a Topic

  • All Topics
  • Patient Eligibility
  • AML
  • Unrelated Donor HCT
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  • ASH 2015
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  • ASH 2018
  • Neuroblastoma