An analysis of 44 patients with early relapsed or refractory follicular lymphoma (FL) shows a significant difference in 3-year event-free survival (EFS) between allogeneic and autologous transplantation (80% vs. 42%, respectively; p<0.015), but only in patients with previous remission duration of ≤12 months. For all patients, regardless of time to relapse, there was no difference in EFS or overall survival between allogeneic and autologous transplantation at 3 years. The authors concluded that “very early relapsed FL may warrant consideration of allogeneic over autologous transplantation in the appropriate setting.”
Lunning MA, et al. Brit J Haematol