How I Assess Comorbidities Prior to HCT

Previous studies have shown the prognostic value of the hematopoietic cell transplantation-comorbidity index (HCT-CI), which measures the prevalence and severity of organ impairments in patients considering HCT. To ensure consistent HCT-CI scores among different evaluators, a web-based training program has been developed that utilizes consistent guidelines and systematic scoring methods. In a test of the training program, 88 randomly selected HCT recipient records at a single institution were confidentially re-scored by evaluators using the web-based program. The inter-evaluator agreement on HCT-CI scores was high, with weighted kappa values of 0.89-0.97.

Sorror ML. Blood