An analysis of 726 cord blood transplants reported to the European cord blood transplant database has found that the cumulative incidence of autoimmune disease developing post-transplant in these patients was 5.0% at 1 year and 6.6% at 5 years. The most commonly occurring diseases were organ-specific autoimmune diseases such as cytopenias, followed by autoimmune diseases of the thyroid. A multivariate analysis revealed that transplantation for a non-malignant disease was the main risk factor for developing an autoimmune disease (p=0.0001).