New Autoimmune Diseases after Cord Blood Transplantation

An analysis of 726 cord blood transplants reported to the European cord blood transplant database has found that the cumulative incidence of autoimmune disease developing post-transplant in these patients was 5.0% at 1 year and 6.6% at 5 years. The most commonly occurring diseases were organ-specific autoimmune diseases such as cytopenias, followed by autoimmune diseases of the thyroid. A multivariate analysis revealed that transplantation for a non-malignant disease was the main risk factor for developing an autoimmune disease (p=0.0001).

Daikeler T, et al. Blood