No Significant Difference in Long-Term Experiences of Marrow, PBSC Donors

A prospective longitudinal study has found no long-term health-related quality-of-life (HRQoL) differences between bone marrow and peripheral blood stem cell (PBSC) donors. In this study by the Blood and Marrow Transplant Clinical Trials Network (BMT CTN), HRQoL experiences of 332 marrow and PBSC donors were evaluated before donation, 48 hours after donation, weekly until fully recovered, and at 6 and 12 months after donation. Although marrow donors reported more physical side effects shortly after donation, there were virtually no longer term differences in the experiences of the two donor groups ≥3 weeks after donation.

Switzer GE, et al. Biol Blood Marrow Transplant