QOL More than 20 Years After HCT for Thalassemia

The long-term health-related quality of life (QOL) of beta-thalassemia patients who underwent allogeneic transplantation is similar to that of the general population, according to a study of 109 patients transplanted in the 1980s and 1990s. Transplant recipients experienced a significant decrease compared to the general population on only one scale, the general health scale. Mental health, education level, marital status, employment status, living arrangements, and birth rate were all comparable between the two cohorts. Transplant recipients scored significantly higher on three of eight QOL scales compared to a matched cohort of 124 patients receiving non-transplant treatment for beta-thalassemia.

La Nasa G, et al. Blood