Review: Factors Affecting Selection of a Pre-HCT Conditioning Regimen

In this review, the authors outline how a patient’s diagnosis, disease status, donor availability, graft source, and patient-related factors such as the presence or absence of comorbid conditions all influence the choice of a pre-transplant conditioning regimen. The authors review the definitions of high-dose, reduced-intensity, and non-myeloablative conditioning regimens, and discuss the toxicities associated with each option.

Gyurkocza B, et al. Blood