In this installment of the "How I Treat" series in the journal Blood, Dr. H. Bobby Gaspar and colleagues describe their treatment algorithms for pediatric patients with severe combined immunodeficiency (SCID). They note that previous research has identified the factors determining successful outcome and survival for SCID, which has improved survival in these patients. They discuss advances in understanding the genetic basis of SCID, and how that knowledge permits tailoring transplant protocols to specific SCID forms and the integration of gene therapies when appropriate, especially in the X-linked and adenosine deaminase (ADA) deficient forms of SCID.
Choose a Topic
- All Topics
- Patient Eligibility
- AML
- Unrelated Donor HCT
- Post-Transplant
- CIBMTR Publications
- GVHD
- ALL
- Lymphomas and CLL
- Preparative Regimens
- Pediatric HCT
- Older Patient HCT
- MDS
- Non-Malignant Disorders
- BMT CTN Publications
- Cord Blood
- Multiple Myeloma
- Sickle Cell Disease
- HLA Matching
- ASH 2015
- ASH 2017
- ASH 2016
- ASH 2020
- CML
- ASH 2018
- Neuroblastoma
Review: How I Treat SCID
Oct 2013