Review: Next Generation Treatment of Acute GVHD

This review describes the recent advances in the understanding of the underlying molecular basis of acute graft-versus-host disease (GVHD). Also discussed are new insights into the roles played by novel cytokines, chemokines, epigenetics, intracellular signaling pathways, and post-translational modifications of proteins in GVHD biology. The authors note that these new insights “provide numerous targets that might be therapeutically exploited.”

Magenau J, et al. Leukemia

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